Heqet Therapeutics pipeline compounds efficiently target multiple pathways via the upregulation of certain non-coding RNAs

Competitive Advantage

Heqet Therapeutics is the first company to advance a microRNA-based therapy for cardiac regeneration into clinical development, addressing the core limitation in current heart failure treatments: the inability to restore lost cardiomyocytes.

Our approach is grounded in a growing industry momentum around non-coding RNAs—validated by recent billion-euro deals such as Novo Nordisk’s acquisition of Cardior and Eli Lilly’s partnership with HAYA Therapeutics. Scientific consensus is also accelerating: the 2024 Nobel Prize in Medicine recognized the discovery of microRNAs, further affirming their therapeutic potential.

The project is led by Prof. Mauro Giacca, a world authority in cardiovascular science, and supported by strategic collaborations with King’s College London and leading CROs—ensuring both scientific depth and translational strength.

Turning the irreversible into regenerative

Discover how we’re rewriting the future of cardiovascular care with non-coding RNA

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Key publications

Mauro Giacca

May 2019

Mauro Giacca

May 2019

Mauro Giacca

January 2017
 

Mauro Giacca

December 2012